Pyridazines and derivatives
![eMolecules 6653-96-9 | Imidazo[1,2-b]pyridazin-6-amine | MFCD10698052 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502139044.JPG-250.jpg)
eMolecules 6653-96-9 | Imidazo[1,2-b]pyridazin-6-amine | MFCD10698052 | 1g
Ambeed | Imidazo[1,2-b]pyridazin-6-amine | 1g | 552624062 | A181962 | 6653-96-9 | MFCD10698052 | 134.142 | C6H6N4
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Medchemexpress LLC Zardaverine | 101975-10-4 | C12H10F2N2O3 | 50 MG
Zardaverine is an orally active and selective PDE3/4 inhibitor with IC50 values of 0.58 uM for PDE3 and 0.17 uM for PDE4. It exhibits potent bronchodilator activity and is effective in reducing inflammation in asthma. Zardaverine also shows antitumor potential by selectively inhibiting the proliferation of HCC cells, inducing apoptosis, and causing cell cycle arrest (G0/G1 phase).
- Orally active and selective PDE3/4 inhibitor
- Potent bronchodilator activity
- Effective in reducing inflammation in asthma
- Selectively inhibits proliferation of HCC cells
- Induces apoptosis and cell cycle arrest (G0/G1 phase)
- Antitumor potential
Aobchem 5-Fluoro-1(2H)-phthalazinone | ≥95% | CAS 23928-50-9 | C8H5FN2O | 500mg
5-Fluoro-1(2H)-phthalazinone | ≥95% | CAS 23928-50-9 | C8H5FN2O | 500mg
Apexbio Technology LLC Phthalazinone pyrazole 880487-62-7 5mg
Phthalazinone pyrazole (CAS 880487-62-7) is a potent selective and orally bioavailable inhibitor of Aurora-A kinase a member of the Aurora kinase family that regulates key processes in cell division Dysregulation of Aurora-A is linked to chromosomal instability and oncogenesis in various tumor types In vitro phthalazinone pyrazole demonstrates strong inhibition of Aurora-A kinase activity with an IC50 of 31 nM while showing minimal effect on Aurora-B kinase at concentrations up to 100 M It inhibits the proliferation of HCT116 Colo205 and MCF-7 cells with IC50 values of 7 8 2 9 and 1 6 M respectively This compound is utilized in research to investigate the role of Aurora-A in cell cycle regulation and cancer biology
TARGETMOL CHEMICALS INC GPI-1046 5MG
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.GPI-1046 is an immunophilin ligand without antibiotic action and attenuates ethanol intake in part through the upregulation of glutamate transporter 1 (GLT1) in PFC and NAc-core. Purity 99.91%
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.4 g/mol | C20H28N2O4 | 50MG
GPI-1046 is a small-molecule immunophilin ligand reported to have neuroprotective effects and to modulate glutamate transporter activity. It is supplied in small laboratory pack sizes, typically as a DMSO solution, for preclinical research use only.
- Chemical formula C20H28N2O4.
- Molecular weight 360.4 g/mol.
- CAS number 186452-09-5.
- Purity 99.8%.
- Available as solution in DMSO and multiple small pack sizes.
- Intended for preclinical research use only.
Medchemexpress LLC MC 1046 (Impurity A of Calcipotriol) | 126860-83-1 | C27H38O3 | 500 UG
MC 1046 is an impurity of Calcipotriol, a Vitamin D3 analog and ligand of VDR-like receptors. Calcipotriol exhibits minimal effects on calcium homeostasis and regulates cell differentiation and proliferation. It also demonstrates antiproliferative activity against various human cancer cell lines, including HL-60, HL60/MX2, MCF-7, T47D, SCC-25, and mouse WEHI-3 cancer cell lines.
- Impurity of Calcipotriol
- Calcipotriol is a Vitamin D3 analog
- Calcipotriol functions as a ligand of VDR-like receptors
- Exhibits minimal effects on calcium homeostasis
- Regulates cell differentiation and proliferation
- Demonstrates antiproliferative activity against various human cancer cell lines
Aobchem 6-Chloropyridazine-3-carboxylic acid | ≥95% | CAS 5096-73-1 | C5H3ClN2O2 | 10g
6-Chloropyridazine-3-carboxylic acid | ≥95% | CAS 5096-73-1 | C5H3ClN2O2 | 10g
eMolecules 4342-43-2 | 2-Methoxycyclohexan-1-amine | Combi-Blocks, Inc. | MFCD11126394 | 129.203 | C7H15NO | 95.000 | COC1CCCCC1N | 1g | 603139574
2-Methoxycyclohexan-1-amine | Combi-Blocks, Inc. | 4342-43-2 | MFCD11126394 | 129.203 | C7H15NO | 95.000 | COC1CCCCC1N | 1g | 603139574
eMolecules 1445-56-3 | Ambeed | 3-Chloropyridazine-4-carbonitrile | 1g | 572143778 | A547184 | MFCD11040160 | 139.54 | C5H2ClN3
Ambeed | (S)-2-Acetamido-N-methylpropanamide | 1g | 572865828 | A105157 | 19701-83-8 | MFCD00038238 | 144.174 | C6H12N2O2
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eMolecules 303085-53-2 | 6-Chloropyridazine-3-carbaldehyde | Ambeed | MFCD10698041 | 142.540 | C5H3ClN2O | 95.000 | Clc1ccc(C=O)nn1 | 100mg | 528956448
6-Chloropyridazine-3-carbaldehyde | Ambeed | 303085-53-2 | MFCD10698041 | 142.540 | C5H3ClN2O | 95.000 | Clc1ccc(C=O)nn1 | 100mg | 528956448
eMolecules 1677-79-8 | 4-Chloropyridazin-3-ol | ChemScene | MFCD00233956 | 130.530 | C4H3ClN2O | 95.000 | Oc1nnccc1Cl | 25g | 596091461
4-Chloropyridazin-3-ol | ChemScene | 1677-79-8 | MFCD00233956 | 130.530 | C4H3ClN2O | 95.000 | Oc1nnccc1Cl | 25g | 596091461
eMolecules 20744-39-2 | 4-Aminopyridazine | AA Blocks LLC | MFCD00233975 | 95.105 | C4H5N3 | 0.000 | Nc1ccnnc1 | 10g | 784388918
4-Aminopyridazine | AA Blocks LLC | 20744-39-2 | MFCD00233975 | 95.105 | C4H5N3 | 0.000 | Nc1ccnnc1 | 10g | 784388918